![]() ![]() 49ers picks or NFL predictions, be sure to see what SportsLine's resident Niners expert, Micah Roberts, has to say, considering his mastery of picks involving San Francisco. San Francisco is a 10.5-point favorite, while the over/under, or total number of points Vegas thinks will be scored, is 44 in the latest 49ers vs. ![]() New York is 1-1 this season, with a blowout loss to Dallas in the opener and a comeback win over Arizona in Week 2. This tilt is also the home opener for the 49ers after back-to-back road wins. Kyle Shanahan and the 49ers have won 12 consecutive regular season games, and the 49ers will host the New York Giants in Week 3. The San Francisco 49ers will try to continue a historic streak when they take the field on Thursday Night Football. ![]()
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